Reglan (metoclopramide) is a prescription medication used to treat certain conditions that affect the stomach and intestines. It works by increasing muscle contractions in the upper digestive tract, helping food move more easily through the stomach and into the intestines. Doctors often prescribe Reglan for short-term relief of nausea, vomiting, heartburn, and symptoms of gastroparesis — especially in patients with diabetes.
This medication is typically offered in 5mg and 10mg tablets, as well as an oral solution. It’s intended for use only under medical supervision and is not recommended for long-term treatment due to the risk of neurological side effects with extended use.
Directions for Use
Take Reglan exactly as prescribed by your healthcare provider. It is usually taken 30 minutes before meals and at bedtime. Do not exceed the recommended dosage or treatment duration.
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Swallow the tablets whole with a glass of water.
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If using the liquid form, measure the dose carefully using a marked syringe or dose-measuring device.
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If you miss a dose, take it as soon as you remember — unless it’s almost time for the next one. Never double up on doses.
Because Reglan affects how quickly your stomach empties, consistent timing is essential for it to work effectively.
Safety Information
Before starting Reglan, tell your doctor if you’ve ever had:
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Parkinson’s disease or other movement disorders
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Depression or a history of mental health issues
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Kidney or liver disease
Do not take Reglan if you’ve previously had a reaction to metoclopramide or are currently using medications that increase the risk of extrapyramidal symptoms.
This medication should not be used for longer than 12 weeks, except in rare cases. Long-term use increases the risk of tardive dyskinesia — a serious and potentially irreversible movement disorder.
Avoid alcohol while taking Reglan, as it may increase drowsiness or dizziness.
Possible Side Effects
While many patients tolerate Reglan well, some may experience side effects, especially with prolonged use. Common side effects include:
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Drowsiness or fatigue
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Restlessness or agitation
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Diarrhea
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Headache
Serious but less common side effects may include:
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Muscle spasms, especially in the face or neck
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Uncontrolled movements (tardive dyskinesia)
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Depression or suicidal thoughts
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Elevated prolactin levels, which may affect hormone balance
If you experience unusual movements, mood changes, or signs of an allergic reaction (rash, swelling, trouble breathing), seek medical attention immediately.
Clinically reviewed | Based on gastrointestinal and neurology guidelines for metoclopramide use in nausea and gastric motility disorders.
Reglan is typically prescribed at 5mg or 10mg up to four times daily before meals and at bedtime. Treatment should be short-term, and patients should be monitored for side effects like restlessness, dizziness, or involuntary muscle movements.
For related digestive treatments, explore Protonix or Imodium — each used in different types of GI symptom management.
Delia –
I was prescribed Reglan after a rough bout of gastroparesis symptoms that just wouldn’t go away. This medication really helped move things along — literally. I noticed improvement in bloating and that awful full-too-fast feeling within the first week.
One thing to be aware of: I had some mild restlessness at night the first few days. My doctor warned me about this, and it faded pretty quickly, but it’s something to monitor.
Overall, Reglan isn’t a miracle drug, but it made a noticeable difference. Just be sure to stay in close contact with your doctor while taking it — this one isn’t a “set it and forget it” kind of medication.
Rachel Donovan –
I started taking Reglan a few weeks ago to help with persistent nausea tied to my acid reflux. Honestly, I was hesitant at first because I’d read some mixed reviews, but it turned out to be a game changer for me. Within a couple of days, the nausea significantly subsided and I was finally able to eat without that constant queasy feeling.
That said, I did experience a bit of drowsiness in the first few days, but it wasn’t anything unmanageable. I just made sure to take it in the evening rather than during the day. So far, no major side effects.
If you’re struggling with similar issues and nothing else has helped, Reglan is definitely worth discussing with your doctor. It gave me a bit of my normal life back.