Dulcolax

Product Description

Dulcolax (bisacodyl) is a stimulant laxative classified as a prodrug, meaning it becomes active only after metabolic conversion in the body. Once it reaches the alkaline environment of the intestine, bisacodyl undergoes hydrolysis, releasing an active compound that stimulates the mucosa of the large intestine. This leads to increased secretion of intestinal fluids and enhanced peristaltic contractions, which help initiate bowel movements. When taken orally, Dulcolax typically begins working within 6 to 10 hours, making it ideal for overnight relief when used before bedtime. Its dual-route administration (oral or rectal) offers flexible and targeted relief from various forms of constipation.

Safety Information

Indications

Dulcolax is indicated for the relief of acute constipation and is especially helpful in cases of intestinal atony following prolonged bed rest, travel, dietary changes, or environmental shifts. It is also beneficial for elderly patients with reduced colonic motility, individuals with hypotonic bowel function, and patients requiring bowel evacuation prior to diagnostic procedures (such as X-ray or endoscopy), surgeries, or childbirth. In clinical practice, Dulcolax is frequently used when rapid and controlled bowel cleansing is necessary without excessive systemic absorption.

Mode of Application

Dulcolax can be administered orally (per os) or rectally (per rectum), depending on the urgency and nature of the condition. Adults are usually prescribed 1 to 3 enteric-coated tablets at night, or 1 to 2 suppositories inserted rectally for more immediate results. If additional relief is needed, a supplementary oral dose may be taken in the morning—ideally 30 minutes before breakfast. The typical adult dosage ranges from 5 mg to 10 mg per day. For children, the dosage must be determined individually based on age and clinical condition, and always under medical supervision.

Contraindications

Dulcolax should not be used in patients with intestinal obstruction, strangulated hernia, or acute inflammatory abdominal conditions such as appendicitis or diverticulitis. It is also contraindicated in cases of peritonitis, gastrointestinal or uterine bleeding, cystitis, spastic constipation, acute proctitis, acute hemorrhoids, and potassium deficiency. Patients with known hypersensitivity to bisacodyl or any inactive ingredients in the formulation should avoid use. Dulcolax should only be used after consultation with a healthcare provider, particularly in vulnerable groups such as the elderly or those with preexisting gastrointestinal conditions.

Side Effects

While Dulcolax is generally well tolerated, some users may experience mild to moderate side effects, particularly when the medication is used in high doses or for extended periods. The most common adverse reactions include abdominal cramping, spasms, and diarrhea, which may lead to dehydration or temporary electrolyte imbalance. Other gastrointestinal effects may include nausea, vomiting, colitis, rectal discomfort, or the presence of small amounts of blood in the stool. Neurological effects such as dizziness or fainting may occur due to a vasovagal response triggered by intestinal spasms or straining during defecation. In rare cases, hypersensitivity reactions such as angioedema or anaphylaxis have been reported. Patients experiencing severe or persistent side effects should seek immediate medical attention.